Perfusion Pump for Microscope
Vibration-free pump for long term live cell imaging under flow
Vibration-free
No interference on your microscope focus
Incubator-friendly
Keep it inside your microscope incubator chamber
Pulsatile or linear flow? You can choose!
Programmable pump opens a myriad of physiological flow possibilities
Perfusion pump for microscope
If your microscope is surrounded by an incubator chamber, that’s not a problem. The perfusion pump for the microscope is incubator-friendly, withstanding elevated temperatures and humidity without problems.
Vibration-free
The small working distance of objectives demands fine control of environmental perturbations, which can be complex with regular pumps with inherently pulsatile profiles.
Our perfusion pump for the microscope ensures that you can have stable flow without any perturbation in image gathering due to the pump vibrations, providing you with high-quality data acquisition.
Autonomous
This microscope pump is self-contained; that is, it has everything that you will need to culture your cells dynamically: an integrated pump and a flow sensor combined in a way that substantially decreases the number of connectors and tubing! You need to connect it to a computer to control and collect data, and you are all set!
Applications and compatibility
The perfusion pump for the microscope is compatible with organ-on-chip applications, and it is not limited by your chip design or manufacturer.
Applications can include:
Stem Cell Culture
Automated and fail-safe long-term microfluidic cell culture system.
✓ Highly controlled microenvironment
✓ Fail-safe mechanism
✓ Automated sequences
Stem Cell Culture
Blood-brain Barrier on Chip
Plug-and-play instrument pack for long term BBB on a chip study
✓ Relevant microenvironment
✓ Automatized organ-on-chip perfusion
✓ Plug-and-play microfluidic platform
Blood-brain Barrier on Chip
Drug Screening
Organ-on-a-chip technology emerged in the early 21st century as a revolutionary approach to simulate human organ functions in vitro. So, what is an organ-on-a-chip? What are its main applications and advantages? And to what extent is it a promising tool for drug testing and disease modeling? We answer all these questions in the following review.
Drug Screening
Sheer Stress
Cell culture system for shear-sensitive cell lines
✓ Safe Neuron Culture Under Flow
✓ Highly Controlled Microenvironment
✓ Up to 3-week Long Cell Cultures
Sheer Stress
Blood-Vessel-on-Chip Pack
Reproduce physiological flow conditions for vasculature assays
✓ Reproduce Physiological Shear Stress
✓ Unindirectional Flow
✓ Use the Device of Your Preference
Blood Vessel Formation & Occlusion (Atherosclerosis)
Bone-on-a-Chip Pack
Easily mimic the complex bone physiology and extracellular environment
✓ Control Complex Microenvironments
✓ Up to 3-week Long Cell Cultures
✓ Fail-Safe Mechanism
✓ Plug-and-Play Platform
Bone Homeostasis and Disease (Osteoporosis)
Immune Response
Models of Physiology and Disease
And many more!
Chips
PMMA Device Station
From mold development to high-resolution PMMA chip fabrication
✓ Fast process
✓ Multiple applications
✓ Simple and innovative setup
PMMA
Synvivo
Ibidi
Microfluidic ChipShop
And many more!
Other equipment
Microscope incubation chambers
Stage top incubators
CO2 incubators
Reservoirs
The perfusion pump can be connected to any reservoir, from Eppendorfs to large bottles, in fully closed or open systems.
Perfusion pump technical specifications
The perfusion pump’s technical specifications are below. If you have any questions, don’t hesitate to contact us at innovation[at]microfluidic.fr!
| Pressure control | |
|---|---|
| Pressure range | -400 to 600 mbar |
| Pressure stability | 0.2 mbar |
| Air flow rate | 0.1 L/min at atmospheric pressure Possibility to work with higher air flow rates by reducing the pressure range |
| Flow control | |
| Microfluidic flow sensor | Monitoring and feedback loop flow control available |
| Flow rates | From 0.1 µL/min to 5 mL/min |
The cell culture system is compatible with standard incubator conditions (37 oC, 5 % CO2, and 95 % humidity). Electronic components (except flow sensors) should be kept outside the incubator.
What comes inside the box?
When you order the perfusion pump for microscopy, you can expect to receive the motherboard with the desired number of units, the reservoirs, flow sensors, the software, and the cable to connect to the computer, as seen below (the laptop is only illustrative).
Customize your pack
Our instruments can be added to different setups depending on your specific needs. In this light, our microfluidic specialists will advise you on the best instruments and accessories depending on your needs and will accompany you during the system’s setup.
Frequently asked questions
Can the perfusion pump for microscopy be placed inside the CO2 incubator?
Yes, the perfusion pump for microscope can also be used inside the CO2 incubator and on the bench without problems.
Is the perfusion pump for microscopy powered by battery?
No, the perfusion pump for microscope is connected to a computer through a cable, which acts as a power supply.
Do I need a computer to operate the perfusion pump for microscopy?
Yes, the perfusion pump for microscopy requires a computer and software to work. Nonetheless, it does not require a compressed air source.
