Patented technology
Air Bubble-Free Microscope Slide
Micropatterned microscope slides for confocal microscopy
No more air bubbles under a microscope slide
Micropatterns automatically remove air bubbles
No need for valap or paraffin
Seal your sample without exposing your cells to external substances
Quick and easy setup
Simply place your sample in the center of the slide and cover with the coverslip
How our solution for air bubbles under a microscope slide works
A single air bubble unintentionally created when placing a coverslip with your fixed cells on top of the microscope slide can ruin days of work.
Air bubbles can damage the cells, prevent the acquisition of quantifiable data and lower the overall image quality in confocal microscopy.
With these limitations in mind, we specifically designed a micropatterned sample holder to avoid air bubbles under microscope slides. It consists of a glass slide with engraved micropatterns or grooves around the sample visualization area. These micropatterns, which act as capillary barriers, are continuous and help contain the liquid within the area of interest without the formation of air bubbles.
Also, capillary forces secure the coverslip on top of the micropatterns, forgoing the need to add wax or paraffin to seal the slide and prevent evaporation.
The surface of the glass slide and the grooves can be modified to better host different sample types.
References
Image reference: Ed Uthman from Houston, TX, USA, CC BY-SA 2.0, via Wikimedia Commons
Other applications for air bubble-free microscope slides
Some other biological applications also include:
Immunohistology
Clinical diagnostic
Immunofluorescence
Immunohistochemistry
And many more!
Air bubble-free microscope slides
| Technical Specifications | |
|---|---|
| Wetted materials | Glass or thermoplastics (PVD, CVD, PECVD) |
| Dimensions | Micropatterns:
|
| Working volumes | TBD |
Frequently asked questions
Can the working volume of the microscope slides be altered?
Yes, our solution can work with custom volumes. Contact our team for more information.
Do they work with any type of coverslip?
Yes, currently our slides to prevent air bubbles are made on demand, so we can adjust the features to any coverslip dimensions.
Can the shape of the micropatterns and observation chamber be altered?
Yes, contact our team for more information on custom designs.
