Patented technology

Air bubble-free microscope slide

Micropatterned microscope slides for confocal microscopy

No more air bubbles under a microscope slide

Micropatterns automatically remove air bubbles

No Need for Valap or Paraffin

Seal your sample without exposing your cells to external substances

Quick and Easy Setup

Simply place your sample in the center of the slide and cover with the coverslip

How our solution for air bubbles under a microscope slide works

A single air bubble unintentionally created when placing a coverslip with your fixed cells on top of the microscope slide can ruin days of work.

Air bubbles can damage the cells, prevent the acquisition of quantifiable data and lower the overall image quality in confocal microscopy.

With these limitations in mind, we specifically designed a micropatterned sample holder to avoid air bubbles under microscope slides. It consists of a glass slide with engraved micropatterns or grooves around the sample visualization area. These micropatterns, which act as capillary barriers, are continuous and help contain the liquid within the area of interest without the formation of air bubbles.

Also, capillary forces secure the coverslip on top of the micropatterns, forgoing the need to add wax or paraffin to seal the slide and prevent evaporation.

The surface of the glass slide and the grooves can be modified to better host different sample types.

References

Image reference: Ed Uthman from Houston, TX, USA, CC BY-SA 2.0, via Wikimedia Commons

Air bubble-free microscope slides

Technical Specifications
Wetted materials	Glass or thermoplastics (PVD, CVD, PECVD)
Dimensions	Micropatterns: Depth: 100 µm Width: 100 µm Distance between micropatterns: 100 µm
Working volumes	TBD