Inflammatory Bowel Disease Model
Automatically collect important markers of IBD in a relevant in vitro model
Uncover cytokine profile changes in time
Automatically collect time-dependent samples of your IBD model
Mimic pathological conditions of IBD
Relevant and controlled microenvironment under flow
Tailor sample volume to your analysis
Collect volumes from microliters to milliliters
Image Credit: Villi in the small intestine, Paul Appleton, University of Dundee. Licence: Attribution 4.0 International (CC BY 4.0)
IBD pack setup
The inflammatory bowel disease model comprises a fluidic controlling unit (pressure controller, flow sensors, and valves) before the chip that allows high-precision liquid handling. Thus, your cells receive a continuous supply of media and nutrients. At the same time, the addition of immune-relevant cytokine triggers for IBD can be done at the most convenient time through an easily controlled set of valves.
Then, the cytokine release profile over time can be assessed due to a fraction collector connected to the chip outlet. Samples can be automatically collected according to your requirements of time and volume.
The IBD pack typically contains:
Flow sensor (Galileo, MIC)
Software (Galileo user interface)
Automated sampler
Flow controller
3/2 Valves and controller
Microfluidic chip
Falcon reservoirs, connectors, tubing, filters…
Check our precision sampling page for more details.
Compatibility of IBD model
Our inflammatory bowel disease model pack was designed to be compatible with commercially available or homemade chips (specific adaptors might be required) and the most common supernatant assays. If you have a particular chip or assay that is not listed below, please contact us!
Chips
PMMA Device Station
From mold development to high-resolution PMMA chip fabrication
✓ Fast process
✓ Multiple applications
✓ Simple and innovative setup
PMMA
Synvivo
Microfluidic ChipShop
Ibidi
Netri
And many more!
Assays
ELISA
Western blot
SEC
HPLC
Mass Spectrometry
And many more!
Customize your pack
Our packs are fully customizable to fit your needs perfectly. Our specialists and researchers will help you choose the best instruments and accessories and accompany you during the setup of the microfluidic platform until you obtain your first experimental results.
Contact our experts to answer any questions about this fraction collector pack and how it can match your specifications!
Frequently asked questions
Is the setup sterilizable?
Yes, we have developed a simple protocol for sterilization and cleaning that is provided along with the user guide.
Can the setup be placed inside the CO2 incubator?
The chip with the cells can be kept inside the incubator and the flow sensors as well, after treatment upon demand. The electronics, such as the pressure controller and the collection valves, should be kept outside the CO2 incubator.
Can a pack be customized based on my specific application?
Yes! Our experts will establish which instruments are best suited for your application, such as the type of flow sensor or the number of flow controller channels you need to perform your experiment. Contact us using the “talk to our experts” green button above.
Can I buy individual instruments?
Our instruments are in beta testing phase and can be tested as a pack or individually, so get in contact with our team to know how our beta testing program works.
