AUTOMATED SAMPLING
Program your sample collection and forget about it
Collect down to 150 µl per sample
Perfect for temporal resolution
Automated sampling setup
If you have ever worried about overnight sample collection or have had to reschedule a day in the lab to fit the sample collection time within reasonable hours, you understand the value of a fully automated sampling unit. Our automated sampling device was designed to allow you to program your sample collection at the most convenient time.
It is especially adapted for perfusion experiments, in which you have a continuous or intermittent flow and want to collect data points at specific times. Below is presented a schematic using a pressure-driven flow controller, such as the OB1, and a flow sensor connected to a microfluidic chip of your choice.
The chip outlet is then connected to the automated sampling unit (fraction collector), allowing the automatic collection of samples at defined time points. Once the samples are collected, they can be analyzed with the most suitable assay so you can unravel the details of how your molecules were secreted over time, as exemplified by the graph.
The pack contains:
- Flow controller
- Microfluidic flow sensor (eg. Galileo)
- Microfluidic chip of your choice
- Automated sampling unit (fraction collector)
- Software (Galileo user interface)
The automated sampling unit is currently designed to fit 20 Eppendorf tubes and can collect down to 150 µl per sample. However, if you need to collect in larger reservoirs, do not hesitate to contact our team!
Check this application note describing how to set up the automated sampling system.
Automated sampling compatibility and applications
The automated sampling unit is compatible with:
Flow generation
- Pressure-drive flow controllers
- Syringe pumps
Microfluidic chips
- Microfluidic ChipShop
- Homemade devices, PDMS, PMMA, etc.
- Ibidi
- Synvivo
- and more!
Applications and assays
- Spectrometry
- ELISA
- Pharmacokinetics assays
- Immunohistochemical and histopathological characterization
- Toxicity assays
- Albumin reabsorption
- and many more!
Customize your instrument
Our instruments are compatible with standard commercialized chips from different brands.
Our instruments can be added to different setups depending on your specific needs. In this light, our microfluidic specialists will advise you on the best instruments and accessories depending on your needs and will accompany you during the system’s setup.
– Check our other instruments for various applications –
Is the instrument compatible with other reservoirs than Eppendorf tubes?
The current version is only compatible with Eppendorf tubes, but other options are being developed, such as for well-plates. If you need a different type of reservoir, contact us using the “talk to our experts” green button above.
What extra equipment is needed?
Besides the fluid flow equipment, such as the pressure-driven flow controller, flow sensor, and chip, you will need a computer to run the software to program the automated sample collection.
Does it only work with experiments under flow?
The automated sampling unit needs to be connected to a flow generator so the automation of the process is possible. Thus, it is best adapted to microfluidics and perfusion experiments. The experiments can have continuous or intermittent (stop/go) flow.
Funding and Support
The LIFESAVER and LOCAI projects helped develop this instrument. This project is funded by European Union’s H2020-LC-GD-2020-3, grant agreement No. 101036702 (LIFESAVER), the French National Research Agency (ANR), and the German Federal Ministry of Education and Research (BMBF) in the frame of the 1st German-French Joint Call for proposals on Artificial Intelligence.
