Perfusion Pump for Incubator
Culture up to 6 chips inside the incubator with the flow profile that you need
Invubator-friendly
Keep everything neatly inside the incubator
No more mechanical stress
Gentle pressure-driven flow not to squish your cells
Pulsatile or linear flow? Youcan choose
Programmable pump opens a myriad of physiological flow possibilities
Perfusion pump
Incubator-friendly pump
Our perfusion pump was designed to keep the same conditions for your entire system and experiment by putting everything inside the incubator. It can withstand the humidity and temperature of the CO2 incubator for prolonged periods while providing precise flow control over your cells.
Autonomous
This perfusion pump is self-contained.
It has everything you will need to culture your cells dynamically: an integrated pump and a flow sensor to substantially decrease the number of connectors and tubing!
Compact
We kept the footprint of the perfusion pump to the smallest possible amount because we know that incubator space is limited and often shared. Thus, we want to allow you to perform several experiments simultaneously without taking up the entire incubator.
High throughput and modular
Concentrations 1, 2, and 3 in triplicates plus the controls, the number of simultaneous experiments escalates quickly. This high throughput perfusion pump can be stacked up to 6 units. Its modularity ensures the flexibility you need while maintaining robust and reliable results.
Easy to use
Based on users’ feedback, we substantially decreased the tubing you need to use in your experiments. New plug-and-play connections make assembling, disassembling, and cleaning much more accessible, so you don’t need to worry! Less variability in the assembly also favors better reproducibility.
Applications and compatibility
The perfusion pump is compatible with organ-on-a-chip applications, and it is not limited by your chip design or manufacturer.
Applications can include:
Stem Cell Culture
Automated and fail-safe long-term microfluidic cell culture system.
✓ Highly controlled microenvironment
✓ Fail-safe mechanism
✓ Automated sequences
Stem Cell Culture
Blood-brain Barrier on Chip
Plug-and-play instrument pack for long term BBB on a chip study
✓ Relevant microenvironment
✓ Automatized organ-on-chip perfusion
✓ Plug-and-play microfluidic platform
Blood-brain Barrier on Chip
Drug Screening
Organ-on-a-chip technology emerged in the early 21st century as a revolutionary approach to simulate human organ functions in vitro. So, what is an organ-on-a-chip? What are its main applications and advantages? And to what extent is it a promising tool for drug testing and disease modeling? We answer all these questions in the following review.
Drug Screening
Sheer Stress
Cell culture system for shear-sensitive cell lines
✓ Safe Neuron Culture Under Flow
✓ Highly Controlled Microenvironment
✓ Up to 3-week Long Cell Cultures
Sheer Stress
Blood-Vessel-on-Chip Pack
Reproduce physiological flow conditions for vasculature assays
✓ Reproduce Physiological Shear Stress
✓ Unindirectional Flow
✓ Use the Device of Your Preference
Blood Vessel Formation & Occlusion (Atherosclerosis)
Bone-on-a-Chip Pack
Easily mimic the complex bone physiology and extracellular environment
✓ Control Complex Microenvironments
✓ Up to 3-week Long Cell Cultures
✓ Fail-Safe Mechanism
✓ Plug-and-Play Platform
Bone Homeostasis and Disease (Osteoporosis)
Immune Response
Models of Physiology and Disease
And many more!
Chips
PMMA Device Station
From mold development to high-resolution PMMA chip fabrication
✓ Fast process
✓ Multiple applications
✓ Simple and innovative setup
PMMA
Synvivo
Ibidi
Microfluidic ChipShop
And many more!
Assays
TEER
Immunostaining of endothelial cell markers
Albumin reabsorption
3D reconstructions
Perfusion assay, using fluorescent dyes
Pharmacokinetics assays
Immunohistochemical and histopathological characterization
Toxicity assays
And many more!
Perfusion pump technical specifications
The technical specifications of the perfusion pump can be found below.
| Pressure control | |
|---|---|
| Pressure range | 4 Channels (0 to 2000 mbar) |
| Pressure stability | Range from 0 to 5 mL/min |
| Recirculation loop | 4 check valves, polycarbonate, male Luer; compatible with 1/4″-28 standard microfluidic fittings |
| Flow control | |
|---|---|
| Microfluidic flow sensor | Monitoring and feedback loop flow control available |
| Flow rates | From 0.1 µL/min to 5 mL/min |
What comes inside the box?
When you order the perfusion pump, you can expect to receive the motherboard with the desired number of units, the reservoirs, flow sensors, the software, and the cable to connect to the computer, as seen below (the laptop is only illustrative).
Customize your pack
Our instruments can be added to different setups depending on your specific needs. In this light, our microfluidic specialists will advise you on the best instruments and accessories depending on your needs and will accompany you during the system’s setup.
Frequently asked questions
Is the perfusion pump powered by battery?
No, the perfusion pump is connected to a computer through a cable, which acts as a power supply.
Do I need a computer to operate the perfusion pump?
Yes, it requires a computer and software to work. Nonetheless, it does not require a compressed air source.
Which microfluidic chips can be connected to the perfusion pump?
The pump can be connected to any microfluidic chip, employing the right connectors.
