PARALLEL CELL CULTURES UNDER CONTROLLED FLOW
PARALLEL CELL CULTURES EQUIPMENT PACK
Multichannel recirculation and precise flow control inside the incubator
Quickly setup for six or more parallel cell cultures
Automatize parallel cell perfusion independently for up to two weeks
Personalize sequences with our software for great reproducibility
Parallel cell culture pack
Easily shift to microfluidics for your dynamic cell culture with this all-included user-friendly, customizable, and automatable parallel cell culture pack.
The state-of-the-art OB1 flow controller (Elveflow) can be coupled with in line sensors to recirculate the medium for dynamic cell cultures precisely. Thanks to its compact design, you can keep the cells in the incubator while running several medium channels simultaneously and independently.
You may also perform recirculation with our already available instruments: the MUX recirculation (Elveflow) or the application using valves.
Microfluidics can also be used for studying cell-cell interactions.
How we make the setup more compact:
- Reduced dead volume, thanks to recirculation valves mounted directly to the flow sensors
- Less tubing valves that reduces pneumatic tubing by half
- Easier to disconnect and move since there is only one flat cable connecting the valves and the flow sensors
- Elimination of trapped bubbles
This pack allows you to recirculate the medium in your dynamic cell culture providing the ideal conditions for your experiment. The setup consists of an easy to manipulate housing that can be easily put in and out from the incubator. This parallel cell cultures pack combines reproducibility with flexibility to empower your research.
Parallel cell culture pack setup
Our all-in-one pack guarantees perfect compatibility between different instruments so you can start your experiment right away. The system is piloted by a single software that may also be used for other applications. We also provide continuous and full customer support for you to get the best results out of your experiments.
Parallel cell culture pack includes:
- OB1 flow controller (Elveflow)
- Several Eppendorf or falcon reservoirs
- 9 port manifolds
- Recirculation valve system (in development)
- Tubing and luers
- Microfluidic chips
- Can include flow sensors (Elveflow)
- Control and automation software (Elveflow)
- User guide
Why use microfluidics for parallel cell culture
Microfluidics is currently the most efficient method to perform dynamic cell culture and grow cells in physiologically relevant conditions. It provides continuous flow to the cells and allows you to colocalize more than one cell type in the same experiment, an essential aspect of cell-cell interactions.
Microfluidics is also compatible with other biological applications and microscope imaging. As mentioned above, the automatized sequence can also be implemented to keep the recirculation running for long periods. The Microfluidics Innovation Center can also integrate the microfluidic platform, making it even more compact and easy to use. Different chips can be used for the same system to observe different samples in parallel easily.
This pack can be combined with other microfluidic steps after the dynamic cell culture, such as sequential injection of drugs or sampling.
With expertise in microfluidic flow control for more than 10 years, we can provide you with state-of-the-art microfluidic systems. From biology to engineering applications, the Microfluidics Innovation Center is the perfect partner for you to get started with microfluidics.
Customize your pack
Several commercialized and laboratory made microfluidic chip – including from microfluidic ChipShop – have been developed and tested to perform parallel cell cultures. We can include one of them with different surface modifications inside the pack. A chip can also have several separated channels.
Our Packs are fully customizable to your needs. Our microfluidic specialists and researchers will help you choose the best instruments and accessories and accompany you during the setup of the microfluidic platform until you get your first experimental results.
All the instruments are controlled by the same ESI software, allowing workflow automation and easy integration in your program with free available libraries.
– Check our other Packs for various applications –
Funding and Support
The ALTERNATIVE project developments helped develop this pack; this project is funded by the European Union’s H2020-LC-GD-2020-3, grant agreement No. 101037090.
