Smart Culture Tube Rack

Automatic switching between tubes for long cell perfusion experiments

Hassle-free long cell perfusion

Automatic switch between media reservoirs

No risk of air reaching your cells

Smart switch before your tube gets empty

Incubator-friendly

Place your tubes inside the incubator for ideal conditions

A smart rack that automates and protects your experiment

In our quest to push the state-of-the-art and provide researchers with instruments that make their lives more accessible in the lab, we realized that long-term cell perfusion experiments require a lot of preparation to become automated and can quickly go wrong due to clogging or biofouling.

 

Thus, we developed an intelligent rack for cell culture tubes that automates the preparation of long-term cell perfusion experiments aimed at media enrichment, in other words, when a defined volume of media is perfused and collected over and over through time.

 

Our Smart culture tube rack has level sensors that identify the liquid height in the reservoir and define a limit. As the media is perfused out and reaches this limit, the system automatically changes the parameters to start perfusing media from the reservoir that, up until then, was collecting the media.

smart cell culture tubes schematics

Also, suppose there’s an unexpected leakage somewhere in the system. In that case, the intelligent rack will stop the perfusion of media before the air enters the system, preserving your experiment and allowing you to collect data even in a mishap.

 

It is important to note that our cell culture under a flow system allows unidirectional flow over the cells. Check out our perfusion system for more info.

Smart culture tube rack applications

The Smart Rack is compatible with the COincubator and with 15ml conical tubes, but it can be adapted to different volume reservoirs upon request.

It can also be employed in a variety of applications, such as:

stem-cell-on-matrix

Stem Cell Culture

Automated and fail-safe long-term microfluidic cell culture system. 

✓ Highly controlled microenvironment

✓ Fail-safe mechanism

✓ Automated sequences

Stem Cell Culture

Gut-on-a-chip

Gut-on-a-chip pack

Intestinal cells coculture under flow, mimicking the gut physiology

✓ All microfluidic pieces included, quick and easy assembly

✓ Dynamic culture conditions

✓ Advanced in viro/ex vivo

Gut-on-chip

Blood-brain barrier on a chip mouse cappillaries

Blood-brain Barrier on Chip

Plug-and-play instrument pack for long term BBB on a chip study

✓ Relevant microenvironment

✓ Automatized organ-on-chip perfusion

✓ Plug-and-play microfluidic platform

Blood-brain Barrier on Chip

liver-on-chip model mouse tissue

Liver-on-a-chip model

Mimic the liver microenvironment in long term experiments

✓ Improve your reproducibility with physiological culturing conditions

✓ Automated and controlled supply of nutrients in a stable flow

✓ Test different conditions at the same time

Liver-on-chip

lung-cells

Lung-on-a-chip model pack

Perform lung research in a physiologically relevant microenvironment

✓ Culture your lung cells in a physiological air-liquid interface

✓ Continuous and controlled supply of nutrients in a stable flow

✓ Stop losing your cell experiment due to clogging

Lung-on-a-chip

blood-cloth-over-wound

Skin-on-a-chip

Reproduce the dynamic extracellular environment of the skin with ease

✓ Compatible with air-liquid interfaces

✓ Compatible with teer measurements

✓ Compatible with live cell imaging

Skin-on-a-chip

kidney proximal tubule

Kidney-on-a-chip

Physiological microenvironment for a more realistic in vitro kidney model

✓ Physiological flow rates

✓ Use the chip of your preference

✓ Enrich the media with metabolites

Kidney-on-a-chip

bone osteoporosis wellcome collection

Bone-on-a-Chip Pack

Easily mimic the complex bone physiology and extracellular environment

✓ Control complex microenvironments

✓ Up to 3-week long cell cultures

✓ Fail-safe mechanism

✓ Plug-and-play platform

Bone-on-a-chip

neuron culture bioreactor

Neuron Culture Pack - Low Shear Cell Culture

Cell culture system for shear-sensitive cell lines

✓ Safe neuron culture under flow

✓ Highly controlled microenvironment

✓ Up to 3-week long cell cultures

Neuron cell culture – low shear cultures

Microfluidic perfusion for dynamic cell culture
HeLa cell attachment et proliferation assay (intermittent flow at 20µl/min).

Customize your smart culture tube rack

Our instruments are compatible with standard commercialized chips from different brands.

Our instruments can be added to different setups depending on your specific needs. In this light, our microfluidic specialists will advise you on the best instruments and accessories depending on your needs and will accompany you during the system’s setup.

Frequently asked questions

Can the cell culture tubes be placed inside the CO2 incubator?

Yes, we have developed a simple protocol for sterilization and cleaning that is provided along with the user guide.

Yes! Our experts will establish which instruments are best suited for your application, such as the type of flow sensor or the number of flow controller channels you need to perform your experiment. Contact us using the “talk to our experts” green button above.

Yes! Our team can help you design the setup that best fits your application. Check our product section.

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Funding and Support

The LIFESAVER project helped develop this instrument. This project is funded by the European Union’s H2020-LC-GD-2020-3, grant agreement No. 101036702 (LIFESAVER).

Products & Associated Accessories

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