qPCR for the diagnosis of urinary tract infection: FIT-UTI
This project is completed now. If interested, feel free to contact us.
Fully integrated technology based on qPCR for the diagnosis of urinary tract infection: introduction
UTI diagnosis: project description
Urinary tract infection (UTI) is a symptomatic bacterial infection within the urinary tract. It is estimated that 15% of all community-prescribed antibiotics in some EU countries are dispensed for UTI [1].
Within this FIT-UTI project, a novel and proprietary lab-on-a-chip system integrating urine sample pre-treatment and quantitative polymerase chain reaction (qPCR) for bacteria gene recognition in point-of-care UTI diagnostics will be developed.
This project will be based on Elvesys’ proprietary FASTGENE technology. The prototype will be expected to perform bacteria filtration, lysis, DNA extraction, and PCR full-automatically. It will provide a reliable diagnosis of UTI from the urine sample input to fluorescence readout in less than 15 minutes.
This technology can also be extended to other disease diagnostics, thus contributing to solving the current EU need for fast point-of-care diagnostic technologie
1. Guidelines on urological infections, European Association of Urology, 2015.
This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No 750999 (FIT-UTI project).
Researcher
Dr. Sisi LI
Research Associate
- Research fellow of NTU & SIMTech, A*STAR, Singapore
- PhD & Postdoc of CNRS-ENS-UMPC, France
- 14 publications- 2 patents- H index 7
Areas of expertise:
Microfluidics, Micro & Nanoengineering of cell microenvironment, Cell biology, MEMS, Biomaterials.
