• Scientifically sound, practicably implementable non-animal solutions readily deployable to aid in meaningful safety assessment of chemicals.

⇒ Organ-on-chip aims to recreate an organ, or part of an organ, at the microscale. The effect of chemicals on health can be studied in these model organs, which can even be connected.

• Uptake and commercial exploitation of the developed safety assessment approaches, products, and services.

⇒ Our focus will be on developing user-friendly and easy-to-use tools for organ-on-chip technology, with the clear objective of democratizing this technique for evaluating new molecules. As an industrial partner, we are experienced in developing innovative products aligned with the expectations of the end users, and we will help you design a tool suitable for commercialization.

• Contribution to the Three Rs (3Rs) principles (‘Replacement’, ‘Reduction’, ‘Refinement’), with a particular emphasis on the ‘Replacement’ opportunities.

⇒ Organ-on-chip allows us to model the natural body barriers in a much more physiologically relevant way than conventional cell culture (e.g., the possibility of inducing shear stress on cells to control the microenvironment of the cells very precisely). They offer a promising way to replace animal chemical and drug evaluation testing.