Label-free cell sorting for malaria detection: LAPASO
This project aims to develop a label-free microfluidic cell sorting device to detect parasites such as malaria in blood samples rapidly.
The final aim of this project is to ensure the spreading of our low-cost lab-on-a-chip into emerging countries.
This project is completed now. If interested, feel free to contact us.
The first lab-on-a-chip for low-cost malaria detection: introduction
The MIC is a full partner of the Lapaso European consortium. Microfluidic particle fractionation based on the inherent properties of cells, microorganisms, and organelles offers significant improvements over conventional techniques in ease of handling and use, speed, and cost reduction.
Our objective is to consolidate the field at the European level and create a unique, comprehensive training program based on solid experimental and theoretical foundations.
LAPASO provides a unique training opportunity for 15 fellows in a highly interdisciplinary and intersectoral environment.
Our overarching scientific objective is to advance diagnostics for a wide range of critical medical conditions using cutting-edge microfluidics and nanobiotechnology integration.
Microfluidic label-free cell sorting: project description
Developing novel label-free cell sorting schemes based on particle morphology, deformability, and dielectric properties combines experimental approaches with advanced modeling techniques.
The study of morphology-sensitive sorting to learn about bacterial pathogenesis and to develop devices that provide improved diagnostics of bacterial disease and information about subpopulations to assist targeted treatment.
The study of morphology and deformability-sensitive sorting to enrich parasites and parasite-infected cells for more straightforward and quicker diagnostics of severe diseases. The study of the physical characteristics of rare cells to develop optimum sorting schemes for extracting rare stem cells from bone marrow.
A Pack has been assembled for label-free cell sorting.
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 607350 (LAPASO).
Do you need more information ? You can have a look at Alessandra’s review about optical detection in microfluidics.
