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Missions 2026-2027 ordered by microfluidic relevance

Horizon Europe Missions

Work Programme 2026-2027

Writer

Celeste Chidiac, PhD

Keywords

Microfluidic Devices, Intelligent Microfluidics, Artificial Intelligence, Machine Learning

Opening

Dec 2025, Feb/Nov 2026, Feb 2027

Deadline

Ap/Sep/Oct 2026, Feb/Sep/Oct 2027

Keywords

Intelligent Microfluidics

Deep Learning

Microfluidic Devices

Artificial Intelligence

Machine Learning

climate resilience

Virtual Human Twins

soil health

circular logistics city

ocean restoration

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Horizon Europe Missions 2026-2027
Calls ordered by microfluidic relevance

We have sorted the calls for projects from Missions 2026-2027 according to the impact that microfluidics can have on the calls for projects and related topics. We are sharing our analysis in case it can help you with project funding efforts. And, of course, if our expertise can be of use to you, we would be delighted to discuss it further.

CALL EU Missions Horizon-Europe-work-programme 2026

How to read the stars in terms of % of microfluidic technologies’ relevance for the call:

By microfluidic relevance, we mean the relevance of using microfluidic technologies for the topic cited. But also, to a lesser extent, what a microfluidic laboratory or SME could contribute to the topic (mainly for calls with low relevance to microfluidic technologies).

Relevance (%)

90-100

80-89

70-79

60-69

50-59

40-49

30-39

20-29

10-19

0-9

Relevance (*)

*****

****

***

**

*

–

– –

– – – 

– – – – 

– – – – –

Quick selection guide (where Microfluidics should be prioritized)

  1. CANCER early detection & modelling: CANCER‑02 (2026), CANCER‑01 (2026), CANCER‑03 (2027) – leverage Microfluidics’ droplet microfluidics, organ‑on‑chip, and regulated diagnostic workflows.
  2. WATER & WASTEWATER: CLIMA‑CIT‑CCRI‑02 (2027), OCEAN‑02 (2026), OCEAN‑05 (2026) – strong fit for in‑situ µ‑sensing, micro‑reactors, eDNA‑on‑chip feeding Digital Twins.
  3. SOIL & HEALTH: SOIL‑02 (2026), SOIL‑CANCER (2027), SOIL‑02 (2027) – soil‑on‑chip, AMR assays, µ‑bioreactors.


The work programme draft can be found in the following link: EU Missions

(Details for all topics are provided below, ordered by decreasing microfluidic relevance)

Discover more!

Horizon Europe Missions 2026-2027 Calls ordered by microfluidic relevance

Download the MISSIONS 2026-2027 Call Calendar

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★★★★★ HORIZON‑MISS‑2026‑02‑CANCER‑02 – MICROBIOME FOR EARLY CANCER PREDICTION BEFORE THE ONSET OF DISEASE

  • Type of action: RIA. Call: Supporting the implementation of the Cancer Mission (2026).
  • Opening 10 Dec 2025, deadline 15 Sep 2026
  • Budget (topic, M€): 15.00. #projects: 1
  • Scientific focus
    • Advance hypothesis‑driven and data‑driven use of human microbiome signals to predict cancer risk pre‑symptomatically.
    • Integrate longitudinal sampling, robust biomarkers, and clinically actionable stratification.
    • Support evidence pipelines that can translate to screening and prevention programs.
  • Why microfluidics matters
    • Droplet microfluidics for ultra‑high‑throughput multi‑omic library preparation (low‑input stool/saliva/blood) to detect weak signals early.
    • Lab‑on‑chip sample‑to‑answer workflows (nucleic‑acid extraction, amplification, CRISPR/antibody detection) to cut cost/time per test.
    • On‑chip single‑cell microbiome & host‑cell co‑analysis to find functional signatures preceding tumorigenesis.
    • Fieldable µ-samplers and stabilization cartridges enabling home/primary‑care sampling and federated clinical validation.
    • QC/calibration protocols for preanalytical control, supporting reproducibility across centers.

★★★★★ HORIZON‑MISS‑2026‑02‑CANCER‑01 – VIRTUAL HUMAN TWIN (VHT) MODELS FOR CANCER RESEARCH

  • Type of action: RIA. Call: Cancer Mission (2026).
  • Opening 10 Dec 2025, deadline 15 Sep 2026
  • Budget: 35.00 M€. Expected/project: 8.00-9.00 M€. #projects: 4.
  • Scientific focus
    • Build computable Virtual Human Twin assets linking multi-scale biology to clinical endpoints in oncology.
    • Federate data/models for prediction, decision support, and in‑silico trials. 
  • Why microfluidics matters
    • Organ‑on‑chip (MPS) platforms provide physiologically anchored parameters to inform/validate VHT models (PK/PD, immune‑tumor crosstalk, micro‑metastasis).
    • Tumor‑on‑chip with immune‑on‑chip co-cultures to generate mechanistic data under controlled flow and gradients.
    • Microfabrication of polymer chips tailored to partner lab protocols; GLP‑ready workflows and training.
    • Bridges in‑vitro ↔ in‑silico, reducing animal reliance and enabling patient‑avatar calibration.

★★★★★ HORIZON‑MISS‑2027‑07‑CLIMA‑CIT‑CCRI‑02 – DEPLOYING INNOVATIVE WASTEWATER MANAGEMENT, TREATMENT AND VALORISATION SOLUTIONS IN EUROPEAN CITIES AND REGIONS IN THE CONTEXT OF CLIMATE CHANGE

  • Type of action: IA. Call: Joint call Cities × Adaptation (2027).
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Budget: 28.50 M€. Expected: Around 9.50 M€. #projects: 3.
  • Scientific focus
    • City/regional demonstrators for next‑gen wastewater solutions resilient to climate‑stress (peaks, droughts, heat).
    • Integration with circular‑economy and pollutant control goals; multi‑stakeholder deployment.
  • Why microfluidics matters
    • On‑line microfluidic sensors for PFAS, nutrients, pharmaceuticals, AMR markers (low‑power, low‑reagent).
    • Chip micro‑reactors (advanced oxidation, catalytic/reagent‑free) to intensify treatment with small footprints.
    • µ‑bioreactors for microbial resource recovery (biopolymers, VFAs) under controlled shear/oxygen transfer.
    • Distributed µ‑samplers + harmonised QC enable high‑resolution spatiotemporal control and Digital‑Twin feeds.

★★★★★ HORIZON‑MISS‑2026‑05‑SOIL‑02 – ANTIMICROBIAL RESISTANCE AND ANTIBIOTIC BIOSYNTHESIS IN SOILS: DEVELOPING KEY UNDERSTANDING AND COUNTERACTIVE STRATEGIES USING A ONE‑HEALTH APPROACH

  • Type of action: RIA. Call: Soil Mission (2026).
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Budget: 13.00 M€. Expected: Around 6.50 M€. #projects: 2.
  • Scientific focus
    • Elucidate soil AMR dynamics and antibiotic biosynthesis pathways in a One‑Health frame; develop countermeasures.
  • Why microfluidics matters
    • Soil‑on‑chip microcosms to track horizontal gene transfer and biofilm evolution under realistic gradients.
    • Droplet microfluidics for ultrahigh‑throughput antimicrobial screening & resistance fitness mapping.
    • On‑chip nucleic‑acid prep for eDNA/eRNA to quantify resistomes with minimal inhibitors.
    • Portable µ‑assay kits for field phenotyping; training modules for labs in associated regions.

★★★★★ HORIZON‑MISS‑2027‑06‑SOIL‑CANCER – LIVING LABS TO MONITOR AND MITIGATE CARCINOGENIC SUBSTANCES IN AND ORIGINATING FROM SOILS: EVALUATING THEIR EFFECTS ON HUMAN CANCER RISKS

  • Type of action: RIA. Call: Joint call Soil × Cancer (2027).
  • Opening 09/10 Dec 2025, deadline 21 Sep 2027
  • Budget: 24.00 M€. Expected: Around 12.00 M€. #projects: 2.
  • Scientific focus
    • Living‑labs to monitor fluxes of carcinogens from soils, assess exposure pathways, and co‑develop mitigation.
  • Why microfluidics matters
    • Fieldable micro‑samplers for volatile/semi‑volatile organics & metals (preconcentration, micro‑extraction).
    • Organ‑on‑chip exposure models (liver, lung, gut) to link dose → effect at realistic exposure kinetics.
    • Lab‑on‑chip analytics for rapid hotspot screening and community engagement; training for local labs.

★★★★ HORIZON‑MISS‑2026‑03‑OCEAN‑02 – ADDRESSING AQUATIC POLLUTION AND BIODIVERSITY LOSS THROUGH NATURE POSITIVE SOLUTIONS FROM SOURCE TO SEA

  • Type of action: IA. Call: Restore our Ocean & Waters (2026).
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Budget: 32.00 M€. Expected: 7.00-8.00 M€. #projects: 4.
  • Scientific focus
    • Demonstrate catchment‑to‑coast interventions that curb pollution and restore biodiversity via nature‑positive measures.
  • Microfluidics value
    • In‑situ microfluidic sensors (nutrients, PFAS, pharma) feeding source‑to‑sea control loops.
    • eDNA‑on‑chip modules to track biodiversity response to interventions in near‑real‑time.
    • Rugged autonomous µ‑nodes for dense monitoring networks supporting evaluation & replication.

★★★★ HORIZON‑MISS‑2026‑05‑SOIL‑01 – MONITORING SOIL HEALTH IN PRACTICE: EQUIPPING STAKEHOLDERS TO SAMPLE, ANALYSE, AND INTERPRET SOIL HEALTH INDICATORS

  • Type of action: CSA. Call: Soil Mission (2026).
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Budget: 5.00 M€. #projects: 1.
  • Scientific focus
    • Deployment support for sampling/analysis/interpretation of soil indicators; capacity building & harmonisation.
  • Microfluidics value
    • Portable lab‑on‑chip kits (nitrate, phosphate, TOC, enzymes) with training curricula for practitioners.
    • Micro‑prep cartridges to remove soil inhibitors; QA/QC protocols ensuring inter‑lab comparability.

★★★★ HORIZON‑MISS‑2027‑05‑SOIL‑02 – INNOVATIVE BIOTECHNOLOGIES TO RESTORE SOIL HEALTH AND IMPROVE AGRICULTURAL COMPETITIVENESS AND RESILIENCE

  • Type of action: IA. Call: Soil Mission (2027).
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Budget: 12.80 M€. Expected: Around 6.40 M€. #projects: 2.
  • Scientific focus
    • Demonstrate soil biotech solutions that restore functions and boost resilience/competitiveness.
  • Microfluidics value
    • µ‑bioreactors for microbial consortia optimisation; droplet screens for enzyme/strain selection.
    • Soil‑on‑chip assays to quantify function recovery under controlled moisture/oxygen gradients.

★★★★ HORIZON‑MISS‑2027‑03‑OCEAN‑02 – CIRCULARITY OF SEAFOOD SUPPLY CHAIN

  • Type of action: IA. Call: Restore our Ocean & Waters (2027).
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Budget: 31.10 M€. Expected: 7.20-7.775 M€. #projects: 4.
  • Scientific focus
    • End‑to‑end circularity demonstrators (quality, safety, waste valorisation, traceability).
  • Microfluidics value
    • On‑line µ‑sensors for freshness/pathogens/toxins in processing lines.
    • Chip fractionation for valorising side‑streams (proteins, omega‑oils) with low energy use.

★★★★ HORIZON‑MISS‑2027‑02‑CANCER‑03 – PHASE 1 INCLUDING FIRST‑IN‑HUMAN CLINICAL TRIALS TO TEST BIOMARKER‑GUIDED MEDICINES FOR PATIENTS WITH RARE CANCERS OR VERY RARE CANCER SUBTYPES

  • Type: RIA. Call: Cancer Mission (2027).
  • Opening 09/10 Dec 2025, deadline 21 Sep 2027
  • Budget: 25.00 M€. Expected: 7.00-9.00 M€. #projects: 3.
  • Scientific focus
    • Early‑phase biomarker‑guided trials for rare cancers; accelerate clinical translation.
  • Microfluidics value
    • Microfluidic CTC/EV assays and rare‑cell omics to refine inclusion/stratification and PK/PD sampling.
    • Ex‑vivo tumor‑on‑chip chemosensitivity to inform dose/schedule hypotheses.

★★★★ HORIZON‑MISS‑2027‑02‑CANCER‑01 – LEVERAGING FUNCTIONAL GENOMICS TO REVEAL NOVEL TARGETS FOR CANCER TREATMENT

  • Type: RIA. Call: Cancer Mission (2027).
  • Opening 09/10 Dec 2025, deadline 21 Sep 2027
  • Budget: 33.30 M€. Expected: 7.00-8.00 M€. #projects: 4.

Scientific focus

  • High‑content functional genomics to discover actionable targets across tumours.

Microfluidics value

  • Droplet‑based CRISPR screens and single‑cell perturb‑seq on‑chip to map target dependencies efficiently.

★★★ HORIZON‑MISS‑2026‑03‑OCEAN‑05 – REGIONAL (SEA‑BASINS) COMPONENTS OF THE EU DIGITAL TWIN OCEAN

  • Type: IA. Call: Restore our Ocean & Waters (2026).
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Budget: 20.00 M€. Expected: Around 5.00 M€. #projects: 4.
  • Scientific focus: Regional building blocks for the EU Digital Twin Ocean with data/assimilation & services.
  • Microfluidics value: µ‑sensor arrays and autonomous micro‑samplers as cost‑effective data feeds; QA/QC methods for harmonised ingestion.

★★★ HORIZON‑MISS‑2026‑01‑CLIMA‑06 – IMPROVING CLIMATE RESILIENCE OF NAVIGABLE INLAND WATERWAYS, THEIR SURROUNDINGS AND RELATED WATER INFRASTRUCTURE

  • Type: RIA. Call: Adaptation to Climate Change (2026).
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Budget: 12.00 M€. Expected: Around 6.00 M€. #projects: 2.
  • Scientific focus
    • Risk assessment & modelling for EU waterways (droughts, floods, compound events) and nature‑based resilience options; stakeholder coordination.
  • Microfluidics value
    • In‑situ microfluidic water‑quality nodes (nutrients, contaminants) to complement hydraulic/ecological indicators.
    • µ‑lab workflows for rapid event monitoring during low‑flow/high‑flow extremes.

★★★ HORIZON‑MISS‑2027‑03‑OCEAN‑03 – GREEN, CIRCULAR AND RESILIENT HARBOURS

  • Type: IA. Budget: 12.00 M€. Expected: 5.50-6.00 M€. #projects: 2.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus: Demonstrate low‑impact, circular, and climate‑resilient port operations/ infrastructures.
  • Microfluidics: µ‑sensors for stormwater/industrial discharges, micro‑reactors for polishing side‑streams, compact bioassays for eco‑tox risk.

★★★ HORIZON‑MISS‑2027‑03‑OCEAN‑01 – INCREASING RIPARIAN AND COASTAL AREAS RESILIENCE TO CLIMATE CHANGE, INCLUDING IN WATERFRONT CITIES AND ISLANDS

  • Type: IA. Budget: 36.00 M€. Expected: 8.00-9.00 M€. #projects: 4.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus: Place‑based resilience demonstrators for coasts & riparian zones.
  • Microfluidics: Dense, low‑power µ‑monitoring (salinity/nutrients/harmful agents) to steer NbS performance tracking.

★★★ HORIZON‑MISS‑2026‑03‑OCEAN‑04 – TOWARDS A EUROPEAN NETWORK OF OCEAN TECHNOLOGY TESTING SITES

  • Type: CSA. Budget: 3.00 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Coordination of test sites and access/use frameworks.
  • Microfluidics: Position µ‑sensor and sampler prototypes for pre‑normative testing and certification pathways.

★★★ HORIZON‑MISS‑2026‑03‑OCEAN‑03 – BY FISHERS, FOR FISHERS: CO‑MANAGEMENT OF MARINE AND FRESHWATERS ECOSYSTEMS AND RESOURCES

  • Type: IA. Budget: 32.00 M€. Expected: 7.00-8.00 M€. #projects: 4.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Co‑management demonstrators by/with fishers and communities.
  • Microfluidics: Deck‑ready µ‑assays for pathogens/biotoxins and environmental DNA to inform adaptive rules.

★★★ HORIZON‑MISS‑2027‑04‑CIT‑02 – HYDROGEN CITIES

  • Type: CSA. Budget: 5.00 M€. #projects: 1.
  • Opening 09 Feb 2027, deadline 07 Oct 2027
  • Focus: Coordination/road‑mapping for citywide hydrogen deployment.
  • Microfluidics: Niche fit via micro‑channel flow‑field prototyping and electrolyser stack diagnostics training within pilots.

★★★ HORIZON‑MISS‑2027‑05‑SOIL‑01‑TWO‑STAGE – LIVING LABS TO ENHANCE SOIL HEALTH IN CONTINENTAL, BLACK SEA, PANNONIAN AND STEPPIC BIOGEOGRAPHICAL REGIONS

  • Type: RIA. Budget: 24.00 M€. Expected: Around 12.00 M€. #projects: 2.
  • Opening 10 Nov 2026, deadline 16 Feb 2027 (stage 1), 14 Sep 2027 (stage 2)
  • Focus: Regional living labs co‑creating scalable soil‑health solutions.
  • Microfluidics: Field µ‑kits for nutrient/biology indicators; training for local labs and harmonised data capture.

★★ HORIZON‑MISS‑2026‑05‑SOIL‑04 – LEVERAGING LONG‑TERM FIELD EXPERIMENTS AND OTHER DATASETS TO DEVELOP AI‑READY DECISION SUPPORT SYSTEMS FOR SUSTAINABLE SOIL MANAGEMENT

  • Type: IA. Budget: 12.00 M€. Expected: Around 6.00 M€. #projects: 2.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Turn legacy & LTE data into AI‑ready DSS for soil management.
  • Microfluidics: Standardised µ‑sensor data schemas & calibration chains to make field measurements AI‑ingestible.

★★ HORIZON‑MISS‑2026‑03‑OCEAN‑01 – LARGE‑SCALE DEMONSTRATION FOR MAPPING THE DISTRIBUTION AND CONDITION OF MARINE HABITATS TO IMPLEMENT THE NATURE RESTORATION REGULATION

  • Type: IA. Budget: 32.00 M€. Expected: 7.00-8.00 M€. #projects: 4.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Operational habitat mapping & condition assessment at scale.
  • Microfluidics: On‑chip eDNA & µ‑nutrient sensing complementing remote/acoustic methods.

★★ HORIZON‑MISS‑2027‑01‑CLIMA‑02 – RESEARCHING AND APPLYING THE POTENTIAL OF ARTIFICIAL INTELLIGENCE TO FOSTER CLIMATE RESILIENCE AT THE REGIONAL AND LOCAL LEVELS

  • Type: RIA. Budget: 12.00 M€. Expected: Around 3.00 M€. #projects: 4.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus: New AI methods and applications for adaptation planning & operations.
  • Microfluidics: Provide reliable µ‑sensor data streams (validated, uncertainty‑aware) to train/test AI for local resilience.

★★ HORIZON‑MISS‑2027‑05‑SOIL‑02‑TWO‑STAGE – LIVING LABS FOR CO‑CREATING SOLUTIONS TO REDUCE EUTROPHICATION FROM AGRICULTURE

  • Type: RIA. Budget: 24.00 M€. Expected: Around 12.00 M€. #projects: 2.
  • Opening 10 Nov 2026, deadline 16 Feb 2027 (stage 1), 14 Sep 2027 (stage 2)
  • Focus: Co‑designed measures to cut nutrient loads.
  • Microfluidics: µ‑nutrient analyzers (NO3⁻/PO4³⁻/NH4⁺) and micro‑samplers for storm pulses.

★★ HORIZON‑MISS‑2027‑03‑OCEAN‑05 – LARGE‑SCALE DEMONSTRATION FOR BLUE FORESTATION OF EUROPEAN SEA BASINS

  • Type: IA. Budget: 16.00 M€. Expected: 3.50-4.00 M€. #projects: 4.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Demonstrators for macroalgae/seagrass restoration at scale.
  • Microfluidics: µ‑nutrient/CO₂ sensors and biogrowth micro‑assays to optimise planting/maintenance.

★★ HORIZON‑MISS‑2027‑04‑CIT‑01 – INNOVATIVE MICROGRIDS FOR IMPROVED ENERGY SYSTEM INTEGRATION AND EFFICIENCY IN URBAN CONTEXTS

  • Type: IA. Budget: 20.00 M€. Expected: Around 7.00 M€. #projects: 3.
  • Opening 09 Feb 2027, deadline 07 Oct 2027
  • Focus: City microgrids integration and flexibility demonstrators.
  • Microfluidics: Niche via thermal micro‑exchangers for compact CHP/HVAC demonstrators or µ‑sensors for power‑to‑water processes.

★★ HORIZON‑MISS‑2027‑07‑CLIMA‑CIT‑NEB‑01 – URBAN NATURE: SUPPORTING RESTORATION OF URBAN ECOSYSTEMS, ALONG URBAN TRANSPORT NETWORKS AND IN THE BUILT ENVIRONMENT

  • Type: IA. Budget: 40.00 M€. Expected: Around 10.00 M€. #projects: 4.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus: NbS demonstrators in urban/brownfield contexts.
  • Microfluidics: Environmental µ‑sensor networks (soil moisture, pollutants) to steer maintenance & quantify co‑benefits.

★★ HORIZON‑MISS‑2026‑01‑CLIMA‑05 – DEMONSTRATING SOLUTIONS TO PROTECT AND PRESERVE CULTURAL HERITAGE FROM THE IMPACTS OF CLIMATE CHANGE

  • Type: IA. Budget: 21.00 M€. Expected: Around 7.00 M€. #projects: 3.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Multi‑site demos protecting movable/immovable/natural heritage from climate impacts.
  • Microfluidics: µ‑climate & pollutant sensors and micro‑desorption diagnostics for preventive conservation.

★★ HORIZON‑MISS‑2026‑05‑SOIL‑01‑TWO‑STAGE – LIVING LABS TO ENHANCE SOIL HEALTH IN ALPINE AND ATLANTIC BIOGEOGRAPHICAL REGIONS

  • Type: RIA. Budget: 24.00 M€. Expected: Around 12.00 M€. #projects: 2.
  • Opening 09 Dec 2025, deadline 14 Apr 2026 (stage 1), 15 Sep 2026 (stage 2)
  • Focus: Co‑create regional soil‑health innovations.
  • Microfluidics: Field µ‑kits + training for indicator monitoring; integration with living‑lab data platforms.

★★ HORIZON‑MISS‑2026‑05‑SOIL‑02‑TWO‑STAGE – LIVING LABS TO ENHANCE SOIL HEALTH IN MANAGED FORESTS AND IN NATURAL/SEMI‑NATURAL LANDS

  • Type: RIA. Budget: 24.00 M€. Expected: Around 12.00 M€. #projects: 2.
  • Opening 09 Dec 2025, deadline 14 Apr 2026 (stage 1), 15 Sep 2026 (stage 2)
  • Microfluidics: µ‑assays for soil respiration/enzymes; on‑chip pathogen surveillance for forest health.

★ HORIZON‑MISS‑2026‑01‑CLIMA‑03 – STANDARDISING AND SUPPORTING CLIMATE SERVICES FOR CLIMATE ADAPTATION

  • Type: RIA. Budget: 9.19 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Reference datasets/scenarios and standardised climate‑service practices for decision‑making.
  • Microfluidics: Contribute measurement standards & uncertainty for µ‑sensor data streams used by services.

★ HORIZON‑MISS‑2027‑01‑CLIMA‑01 – DEMONSTRATING TRANSFORMATIVE SOLUTIONS TO INCREASE TRANSBORDER CLIMATE RESILIENCE

  • Type: IA. Budget: 72.32 M€. Expected: 10.00-15.00 M€. #projects: 5.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus: Multi‑country adaptation demonstrators on shared risks/systems.
  • Microfluidics: Provide cross‑border comparable µ‑monitoring packages and training.

★ HORIZON‑MISS‑2027‑04‑CIT‑05 – PRE‑COMMERCIAL PROCUREMENT (PCP) FOR CLIMATE‑NEUTRAL CITIES

  • Type: PCP. Budget: 26.82 M€. Expected: 7.00-12.00 M€. #projects: 3.
  • Opening 09 Feb 2027, deadline 07 Oct 2027
  • Focus: PCP boosting net‑zero city solutions.
  • Microfluidics: Target lots related to water quality, health monitoring, building IAQ via µ‑analytics.

– HORIZON‑MISS‑2027‑02‑CANCER‑02 – CLINICAL RESEARCH BY COMPREHENSIVE CANCER INFRASTRUCTURES FOR COMMON CANCERS

  • Type: IA. Budget: 20.00 M€. Expected: 7.00-10.00 M€. #projects: 3.
  • Opening 09/10 Dec 2025, deadline 21 Sep 2027
  • Focus: Multicentre clinical research within CCIs.
  • Microfluidics: Optional companion‑diagnostic microfluidic modules for biomarker workflows.

–  HORIZON‑MISS‑2027‑03‑OCEAN‑04 – TOWARDS COMMUNITY‑DRIVEN BUSINESS MODELS: COASTAL AND FRESHWATERS SUSTAINABLE TOURISM

  • Type: IA. Budget: 6.00 M€. Expected: 1.00-1.50 M€. #projects: 4.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus : Sustainable tourism demonstrators.
  • Microfluidics: Niche via water‑quality micro‑monitoring for bathing waters/ponds.

– – HORIZON‑MISS‑2026‑01‑CLIMA‑04 – BRIDGING THE GAP BETWEEN DISASTER RISK MANAGEMENT AND CLIMATE ADAPTATION

  • Type: CSA. Budget: 5.00 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Methods, guidelines, and joint knowledge across DRM & adaptation communities; ECCA conferences.
  • Microfluidics: Limited; possible inputs on rapid µ‑assays for event exposure assessment.

– – HORIZON‑MISS‑2026‑01‑CLIMA‑02 – FACILITATING IMPLEMENTATION OF ACTIONABLE SOLUTIONS FOR CLIMATE ADAPTATION OF REGIONS AND LOCAL AUTHORITIES

  • Type: CSA. Budget: 5.00 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Systematically harvest/promote actionable adaptation solutions; multilingual access via the Mission platform.
  • Microfluidics: Contribute catalogued µ‑sensor/toolkits and training content.

– – HORIZON‑MISS‑2026‑04‑CIT‑02 – TRANSITION TO LOW‑TEMPERATURE HEATING SOLUTIONS IN MULTI‑APARTMENT BUILDINGS

  • Type: IA. Budget: 18.00 M€. Expected: Around 6.00 M€. #projects: 3.
  • Opening 04 Feb 2026, deadline 08 Oct 2026
  • Focus: Retrofit & system integration for low‑T heating.
  • Microfluidics: Minor; niche micro‑heat‑exchanger R&D for compact solutions.

– – HORIZON‑MISS‑2026‑01‑CLIMA‑01 – NATIONAL ADAPTATION HUBS – BRINGING TOGETHER THE NATIONAL LEVEL WITH THE ENGAGED REGIONAL AND LOCAL LEVELS (MULTI‑LEVEL GOVERNANCE)

  • Type: CSA. Budget: 10.00 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Establish/animate national hubs and grouping schemes; FS to third parties for hubs.
  • Microfluidics: Limited; potential training or standard‑kit inputs to hubs.

– – HORIZON‑MISS‑2026‑04‑CIT‑01 – ENERGY‑EFFICIENT URBAN AND SUB‑URBAN PUBLIC TRANSPORT, COMPLEMENTED BY SHARED MOBILITY

  • Type: IA. Budget: 20.00 M€. #projects: 2.
  • Opening 04 Feb 2026, deadline 08 Oct 2026
  • Focus: Integrated clean mobility deployments.
  • Microfluidics: Minimal; potential air‑quality µ‑sensors in depots/corridors.

– – HORIZON‑MISS‑2026‑06‑CLIMA‑SOIL – JOINT DEMONSTRATION OF SOLUTIONS TO BUILD SOIL RESILIENCE TO EXTREME WEATHER EVENTS AND SUPPORT FOOD SECURITY

  • Type: IA. Budget: 20.00 M€. #projects: 2.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Joint Soil×Climate resilience demos.
  • Microfluidics: Supplementary µ‑monitoring of soil water/quality during extremes.

– – – HORIZON‑MISS‑2026‑01‑CLIMA‑07 – DEMONSTRATING INNOVATIVE FINANCING OF LOCAL ADAPTATION ACTIONS WITH COMBINATION OF PUBLIC FUNDING AND PRIVATE FINANCING

  • Type: IA. Budget: 20.00 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Cascade funding + EIB intermediated lending to blend‑finance local adaptation.
  • Microfluidics: Relevance only if leading µ‑sensor‑enabled local projects needing blended finance.

– – – HORIZON‑MISS‑2027‑05‑SOIL‑03 – LONG‑TERM DRIVERS AND CONSEQUENCES OF SOIL DEGRADATION: LEARNING FROM THE PAST TO IMPROVE FUTURE SOIL HEALTH

  • Type: RIA. Budget: 7.00 M€. #projects: 1.
  • Opening 09 Feb 2027, deadline 16/21 Sep 2027
  • Focus: Historical/LTE evidence on soil degradation trajectories.
  • Microfluidics: Limited; contribute standardised assays for selected indicators.

– – – HORIZON‑MISS‑2026‑05‑SOIL‑03 – ENABLING USER‑CENTRED AND OPEN INNOVATION INITIATIVES TO ENHANCE SOIL HEALTH IN UKRAINE

  • Type: CSA. Budget: 4.50 M€. #projects: 1.
  • Opening 04 Feb 2026, deadline 23 Sep 2026
  • Focus: Capacity/open‑innovation for soil health in Ukraine.
  • Microfluidics: Possible training on low‑cost µ‑kits.

– – – HORIZON‑MISS‑2026‑04‑CIT‑NEB‑B4P‑CCRI‑03 – INTRODUCING CIRCULAR ECONOMY MODELS IN THE CONSTRUCTION SECTOR, FROM BUILDINGS TO CITY SCALE

  • Type: IA. Budget: 47.50 M€. Expected: Around 9.50 M€. #projects: 5.
  • Opening 04 Feb 2026, deadline 08 Oct 2026
  • Focus: Circularity across construction value‑chains.
  • Microfluidics: Marginal; potential IAQ µ‑sensors for healthy‑building KPIs.

– – – HORIZON‑MISS‑2027‑04‑CIT‑CCRI‑04 – ADVANCING CIRCULAR LOGISTICS SOLUTIONS IN CITIES

  • Type: IA. Budget: 22.50 M€. Expected: Around 7.50 M€. #projects: 2.
  • Opening 04 Feb 2026, deadline 08 Oct 2026
  • Focus: Circular city logistics innovations.
  • Microfluidics: Minimal; optional µ‑air/odour monitoring in depots.

– – – HORIZON‑MISS‑2027‑02‑CANCER‑04 – IMPROVING EQUITABLE HEALTH OUTCOMES FOR CANCER PATIENTS THROUGH HEALTH‑ECONOMICS, HEALTH‑SYSTEMS AND OUTCOMES RESEARCH

  • Type: RIA. Budget: 10.00 M€. Expected: 5.00-7.00 M€. #projects: 3.
  • Opening 09/10 Dec 2025, deadline 21 Sep 2027
  • Focus: Outcomes & equity research.
  • Microfluidics: Not core; contribute diagnostics access case studies if relevant.

– – – – HORIZON‑MISS‑2026‑02‑CANCER‑04 – EARLIER AND MORE PRECISE PALLIATIVE CARE

  • Type: RIA. Budget: 15.00 M€. Expected: Around 5.00 M€. #projects: 3.
  • Opening 10 Dec 2025, deadline 15 Sep 2026
  • Microfluidics: Very limited relevance

– – – – HORIZON‑MISS‑2026‑02‑CANCER‑05 – BOOSTING MENTAL HEALTH OF YOUNG CANCER SURVIVORS THROUGH THE ECPDC

  • Type: IA. Budget: 7.00 M€. #projects: 1.
  • Opening 10 Dec 2025, deadline 15 Sep 2026
  • Microfluidics: Outside microfluidics core.

– – – – HORIZON‑MISS‑2026‑02‑CANCER‑07 – IMPROVE THE QUALITY OF LIFE OF OLDER CANCER PATIENTS

  • Type: RIA. Budget: 27.00 M€. Expected: 5.00-6.00 M€. #projects: 5.
  • Opening 10 Dec 2025, deadline 15 Sep 2026
  • Microfluidics: Peripheral.

– – – – HORIZON‑MISS‑2026‑02‑CANCER‑06 – DEVELOPMENT OF A RESEARCH CAPACITY BUILDING PROGRAMME ON CANCER WITH AND FOR UKRAINE

  • Type: CSA. Budget: 5.00 M€. #projects: 1.
  • Opening 10 Dec 2025, deadline 15 Sep 2026
  • Microfluidics: Only if capacity‑building in diagnostic microtechnologies is requested.

– – – – HORIZON‑MISS‑2027‑02‑CANCER‑06 – SUPPORT A YOUNG CANCER SURVIVOR QoL RESEARCH PROGRAMME BY CANCER CHARITIES & FUNDERS

  • Type: CSA. Budget: 3.00 M€. #projects: 1.
  • Opening 09/10 Dec 2025, deadline 21 Sep 2027
  • Microfluidics: Not aligned.

Find all these information in the pdf below

Download

The MIC already brings its expertise in microfluidics to Horizon Europe:

H2020-NMBP-TR-IND-2020

Mission Cancer, Tumor-LN-oC_Tumor-on-chip_Microfluidics Innovation Center_MIC

Tumor-LN-oC

Microfluidic platform to study the interaction of cancer cells with lymphatic tissue

H2020-LC-GD-2020-3

Logo_Lifesaver-Microfluidics-Innovation-Center_Mission Cancer_MIC

LIFESAVER

Toxicology assessment of pharmaceutical products on a placenta-on-chip model

H2020-LC-GD-2020-3

Alternative_Logo_microfluidic_in-vitro-system-biomedical-research-Microfluidics-Innovation-Center_Mission Cancer

ALTERNATIVE

Environmenal analysis using a heart-on-chip tissue model

FAQ - Horizon Europe Missions 2026-2027 ordered by microfluidic relevance

What’s considered top-priority microfluidics for these missions?

Three recurring families:

  • Human-centric: organ-on-chip, single-cell tools, digital droplet assays, data streams for virtual human twins.
  • Environment-centric: microfluidic water sensors, soil microbiome and root-soil interfaces, and compact analyzers for pollutants or pathogens.
  • Systems-level: automated screening systems, miniature bioprocess setups, and durable diagnostic units for field use.

When a subject relies on these factors, we consider it highly relevant. Where microfluidics complements other tech, it’s rated moderate or low – useful yet not key.

  • Climate adaptation & resilience: sensors that spot pollutants fast help communities adjust. Instead of waiting, tiny detectors give heads-up on dangerous germs in the air or water. On-the-go medical tests let people check their well-being without delay.
  • Cancer: tiny lab tumors that act like real ones (tumor-on-chip), check how immunity treatments work, grab rogue cancer cells on the move; steady data feeds for digital body copies.
  • Soil health: tiny root-zone labs, testing microbes fast and wide, field checks that spot nutrients or germs quickly.
  • Climate-neutral & smart cities: Cities tackling climate change use scattered sensors for air and water – smart tools track local conditions while staying simple to fix.
  • Restore oceans & waters: Fix seas and rivers with floating sensors on boats, tiny chips that capture genetic traces from water, coatings that stop gunk buildup, and gear that sips power but runs for ages.

Divide your tasks into two main zones.

Technical core: setting up the platform, checking parts work correctly, and building cartridges or flow systems that can grow, each comes with built-in analysis tools.

Pilot setups roll out at clinics, fields, docks, or towns – measuring expenses per check, how fast outcomes arrive, how often upkeep’s needed, plus the reliability of info.

Mind how systems connect – like APIs or file types – as well as proof of accurate calibrations, along with gear that lasts; get it all sorted right away.

Stick to the science – think mechanisms, biomarkers, shifts in ecosystems, mini-organs grown in labs, new materials. Team up with someone who knows how to build stuff at scale, navigate rules, shape product form, and get things working out in the wild. Together, they fit well – one sees what’s possible, the other makes it happen where it counts.

Pumping up multiplexing despite shaky sample handling.

Overlooking gunk buildup or dirt interference in groundwater, as well as the earth.

Missed upkeep schedule – so who swaps out filters during active use?

Split up info flows that don’t make it to virtual models or live tracking screens.

Yep. The groups pay attention. When squads bring in an expert from the start – shaping both tech and outcomes together – they end up way ahead on practical use and adoption. Over at MIC, those setups tend to succeed twice as often as average team-ups.

When it comes to Horizon-level projects, we shape both technical details and real-world outcomes together. Instead of working solo, we team up to match EU expectations while keeping goals clear.

So three points where we can help:

Spot how your research boosts key areas in clear ways.

Set up the service-style setup: who uses it, how often it runs, what it costs, and how consistently it performs.

Mix device layout with trial targets while linking rollout strategies throughout every part of the proposal.

They’re looking for checks against standard techniques, consistent results across labs, and evidence of the stability of readings over time. Testing under tough conditions – like heat, salt levels, murky water – makes a difference. Throw in the price per test compared to what’s already out there.

With health setups: point out how it matches real-world patient data while working alongside stored biological samples.

For ocean or soil use: show it withstands physical stress and resists corrosion.

Go for modular designs – interchangeable parts, uniform plugs. Toss in real-time data tracking along with error alerts, letting regular users fix issues easily. Built-in repairability becomes a big plus when it’s time to evaluate.

Pick a single project where tiny fluid tech actually reduces risk or cost. Write a brief outline: what’s broken, how small-scale flow fixes it, and early success signs. Next, line up teammates – a real-world test spot, someone sharp on rules and numbers, plus a go-to person for turning results into action. Lock down who does what, then sketch a no-fuss check-up strategy.

MIC might check how the idea works, fine-tune the reasoning, and set up both technical support and real-world effects.

Main-Logo-MIC-PURPLE